Normal Clinical Tissue Alliance

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The Normal Clinical Tissue Alliance was created to provide clinical proteomics information about normal tissues. It was initially conceived as a collaboration between the UCSF Medical School, Lawrence Berkeley Laboratories, the Buck Institute for Aging and the University of British Columbia.
The Normal Clinical Tissue Alliance was created to provide clinical proteomics information about normal tissues. It was initially conceived as a collaboration between the UCSF Medical School, Lawrence Berkeley Laboratories, the Buck Institute for Aging and the University of British Columbia.
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==Mission==
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The NCTA was created to develop and maintain list of proteins that can be detected by current, mass spectrometry-based proteomics experiments, on a tissue-by-tissue basis.
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==Methods==
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These protein lists (proteomes) will be generated directly from mass spectra and the curated to generate the lists given below. The selection of which tissues will be annotated is dependent on the public availability of data and tissue provenance of the data. Lists of proteins in publications will be considered in the curation process, but they will be considered as secondary sources if the raw mass spectrometry data they are based on has not been made publicly available.
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==Clinical human tissues currently under curation==
==Clinical human tissues currently under curation==
The following links are to Excel spreadsheets that contain the lists of proteins for the corresponding normal tissue.
The following links are to Excel spreadsheets that contain the lists of proteins for the corresponding normal tissue.

Revision as of 22:39, 9 February 2008

The Normal Clinical Tissue Alliance was created to provide clinical proteomics information about normal tissues. It was initially conceived as a collaboration between the UCSF Medical School, Lawrence Berkeley Laboratories, the Buck Institute for Aging and the University of British Columbia.

Mission

The NCTA was created to develop and maintain list of proteins that can be detected by current, mass spectrometry-based proteomics experiments, on a tissue-by-tissue basis.

Methods

These protein lists (proteomes) will be generated directly from mass spectra and the curated to generate the lists given below. The selection of which tissues will be annotated is dependent on the public availability of data and tissue provenance of the data. Lists of proteins in publications will be considered in the curation process, but they will be considered as secondary sources if the raw mass spectrometry data they are based on has not been made publicly available.

Clinical human tissues currently under curation

The following links are to Excel spreadsheets that contain the lists of proteins for the corresponding normal tissue.

  1. BTO:0000131, Blood plasma
  2. BTO:0000132, Blood platelets
  3. BTO:0000133, Blood serum
  4. BTO:0000140, Bone
  5. BTO:0000142, Brain
  6. BTO:0000155, Bronchoalveolar lavage
  7. BTO:0000237, Cerebrospinal fluid
  8. CL:0000232, Erythrocytes
  9. BTO:0000502, Gastric fundus
  10. BTO:0001501, Hair
  11. BTO:0000723, Lens
  12. BTO:0001202, Saliva
  13. BTO:0001419, Urine

The following spreadsheets contain the lists of proteins with the plasma proteome removed.

  1. BTO:0000132, Blood platelets
  2. BTO:0000133, Blood serum
  3. BTO:0000140, Bone
  4. BTO:0000142, Brain
  5. BTO:0000155, Bronchoalveolar lavage
  6. BTO:0000237, Cerebrospinal fluid
  7. CL:0000232, Erythrocytes
  8. BTO:0000502, Gastric fundus
  9. BTO:0001501, Hair
  10. BTO:0000723, Lens
  11. BTO:0001202, Saliva
  12. BTO:0001419, Urine
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